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Transcriptomics Services | Dalton Bioanalytics

Your Expert Partner for Advanced Transcriptome Analysis

At Dalton Bioanalytics, we deliver comprehensive transcriptomics solutions powered by next-generation sequencing technology. Our state-of-the-art RNA sequencing and bioinformatics capabilities provide deep insights into gene expression, enabling breakthrough discoveries across pharmaceutical, biotechnology, academic, and agricultural applications.

Diagram of the SAGE (Serial Analysis of Gene Expression) method for transcriptomics studies.

Lowe R, Shirley N, Bleackley M, Dolan S, Shafee T (2017) Transcriptomics technologies. PLoS Comput Biol 13(5): e1005457. https://doi.org/10.1371/journal.pcbi.1005457

Our Comprehensive Multiomics Services with Transcriptomics

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Our Comprehensive Transcriptomics Services

Standard RNA Sequencing

  • Complete transcriptome profiling with unparalleled depth and accuracy

  • Digital gene expression analysis across a wide dynamic range

  • Identification of novel transcripts and splice variants

  • Flexible solutions for both model and non-model organisms

  • Ideal for validation studies and focused research

Small RNA Sequencing

  • Comprehensive profiling of miRNA and other small RNA species

  • Discovery of novel small RNA molecules

  • Regulatory network analysis

  • microRNA expression profiling

Long-Read Isoform Sequencing

  • Full-length transcript analysis

  • Alternative splicing detection

  • Gene fusion identification

  • Complete isoform characterization

Applications and Benefits of Our Metabolomics Services

Drug Development and Biomarker Discovery

 

  • Mechanism of action studies

  • Target identification and validation

  • Biomarker development

  • Safety assessment and toxicology

 

Disease Research

  • Pathway analysis in disease states

  • Differential expression studies

  • Novel therapeutic target identification

  • Disease progression monitoring

Agricultural Advancement

  • Crop improvement research

  • Stress response studies

  • Trait development

  • Pest resistance analysis

Why Choose Dalton Bioanalytics for Transcriptomics?

Technical Excellence

  • Latest NGS platforms for superior data quality

  • Comprehensive quality control at every step

  • Flexible library preparation options

  • Advanced bioinformatics pipelines

Expert Support

  • PhD-level project consultation

  • Custom experimental design

  • Comprehensive data analysis

  • Clear result interpretation

Sample Flexibility

  • We support diverse sample types:

  • Fresh/frozen tissue

  • FFPE samples

  • Cell culture

  • Blood and biofluids

  • Low-input samples

  • Degraded RNA

Sample Types and Requirements

  • High-quality total RNA (RIN > 7)

  • Options for degraded samples (FFPE)

  • Various input amounts (10 pg - 1 µg)

  • Comprehensive QC reports

Frequently Asked Questions

Q: What is the difference between bulk RNA-seq and single-cell RNA-seq?

A: Bulk RNA-seq provides average expression profiles across all cells in a sample, while single-cell RNA-seq reveals individual cell transcriptomes, enabling the study of cellular heterogeneity and rare cell populations.

Q: Do you offer solutions for degraded RNA samples?

A: Yes, we have specialized protocols for challenging samples, including FFPE tissue and partially degraded RNA, ensuring quality data even from compromised samples.

Q: What bioinformatics support do you provide?

A: Our comprehensive bioinformatics services include data QC, alignment, differential expression analysis, pathway analysis, and customized reporting to meet your research needs.

Ready to Advance Your Transcriptomics Research?

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